GRADUATE ALUMNI: Yanling Xu
Entered program Fall 2002
Completed Program Spring 2006
Ph.D. Thesis
Education
2002 – 2006 Ph.D. in Pharmacology
Department of Pharmacology
University of California, Irvine
1999 – 2002 M.S. in Anatomy & Cell Biology
Indiana University, Indianapolis, IN
1997−1999 M.S. in Pharmacology
National University of Singapore, Singapore
1991−1996 MD in Clinical Medicine
Shanghai Medical University, P.R. China
Research Interests
Neuropeptide S (NPS) and its cognate G protein coupled receptor (GPCR), the NPS receptor (NPSR), is a newly deorphanized GPCR system. Because it has been discovered very recently, little is known about the function of the NPS/NPSR system. My research project is to decipher the pharmacological characteristics, anatomical distribution and some of the physiological functions of this novel neuropeptide system.
Honors and Awards
Graduate student fellowship (2004), Graduate student travel award (2004)
Publications
Yanling Xu, Rainer K. Reinscheid, Salvador Huitron−Resendiz, Stewart D. Clark, Zhiwei Wang, Steven H. Lin, Fernando A, Brucher, Joanne Zeng, Nga K, Ly, Steven J. Henriksen, Luis de Lecea, and Olivier Civelli. Neuropeptide S: a neuropeptide promotes arousal and anxiolytic−like behavior. Neuron, 2004 August 19; 43: 487−497.
Yanling Xu, Valerie R, Jackson, Olivier Civelli. Orphan G−protein coupled receptor and obesity. European Journal of Pharmacology (In Press).
Yanling Xu, Youssef Sari, Feng C. Zhou. Selective serotonin reuptake inhibitor disrupts organization of thalamocortical somatosensory barrels during development. Brain Res Dev Brain Res. 2004 Jun 21;150(2):151−61
Conferences
2004 Y. Xu, R.K. Reinscheid, S.H. Lin, Z. Wang, J. zheng, N.K.Ly, O.Civelli. The pharmacology and distribution of neuropeptide S system. Annual Meeting of Society for Neuroscience. San Diego.
2004 R.K.Reinscheid, Y. Xu, C.D. Stewart, S, Huitron−Resendiz, S.J.Henriksen, L. de Lecea, F.A. Brucher, O.Civelli. Physiological functions and behavioral effects of neuropeptide S. Annual Meeting of Society for Neuroscience. San Diego.
2003 Y. Xu, R.K. Reinscheid, S.H. Lin, Z. Wang, J. zheng, N.K.Ly, O.Civelli. Neuropeptide S: A natural ligand of orphan G−protein coupled receptor. Annual Meeting of Society for Neuroscience, New Orland,
2001 Y. Xu, Feng C. Zhou. Paroxetine treatment alters the organization of thalamic vibrissae afferent in somatosensory cortex in postnatal rats. Annual Meeting of Society for Neuroscience, San Diego,
2000 Y. Xu, Feng C. Zhou. Levels of 5−HT and 5−HIAA in various embryonic tissues in rats. Annual Meeting of Society for Neuroscience, New Orland,
1998 Y. Xu, C.H. Tan, H.S. Lee B. Yoe, H Yoe. Serotonin and tryptophan in heroin withdrawal patients. 8th International Congress of Pharmacology, MÜchen, Germany.
